List of Publications

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2007

61
Fraser MacMillan
Recent Developments in Biomolecular EPR Spectroscopy
Biophysical Chemistry, Invited Review (2007)


60
Fraser MacMillan & Petra Hellwig
Direct interaction of the high affinity Q_H^-. ubisemiquinone in quinol oxidase (bo₃) from Escherichia coli with a histidine residue in the Asp75His mutant as studied by EPR spectroscopy
J. Bio. Chem., Manuscript being submitted (2007)


59
Fraser MacMillan & Kevin Redding
Determination of the distance between the photo-accumulated chlorophyll and quinone radicals in Photosystem I
J. Bio. Chem., Manuscript being submitted (2007)


58
D. Barthelme, U. Scheele, S. Dinkelaker, A. Janoschka, F. MacMillan, S.-V. Albers, A.J.M. Driessen, M. Salamone-Stagni, E. Bill, W. Meyer-Klaucke, V. Schuenemann, & R. Tampe
Structural organisation of essential iron-sulfur clusters in the evolutionarily highly conserved ATP-binding cassette protein ABCE1
J. Bio. Chem., Manuscript accepted (2007)


57
T.Wenz, R. Covian, P. Hellwig, F. MacMillan, B. Meunier, B. L. Trumpower & C. Hunte
Mutational Analysis of Cytoxchrome c at the Ubiquinol Oxidation Site of Yeast Complex III
J. Bio. Chem., 282, 3977-3988 (2007)

2006

56
Jörg Fritscher, Thomas Prisner & Fraser MacMillan
Theoretical investigation of Q_A^-.-ligand interactions in bacterial reaction centres of Rhodobacter sphaeroides

Appl. Magn. Reson., 30, 251-268 (2006)


55
Daniela Mooser, Oliver Maneg, Fraser MacMillan, Francesco Malatesta, Tewfik Soulimane & Bernd Ludwig
The Menaquinol-oxidizing Cytochrome bc Complex from Thermus thermophilus: Protein Domains and Subunits
Biochim. Biophys. Acta, 1757, 1084-1095 (2006)


54
Tina Wenz, Petra Hellwig, Fraser MacMillan, Brigitte Meunier & Carola Hunte
Mutational analysis of E272 of the mitochondrial complex III - Influence on the formation of the enzyme substrate complex
Biochemistry, 45, 9042-9052 (2006)


53
S. Kacprzak, M. Kaupp & F. MacMillan
Protein-cofactor interactions and EPR parameters for the Q_H quinol binding site of Quinol Oxidase. A density functional study
J. Amer. Chem. Soc., 128 5659-5671 (2006)


52
Fraser MacMillan,* Kerstin Budiman, Heike Angerer & Hartmut Michel
The role of tryptophan 272 in the Paracoccus denitrificans Cytochrome c Oxidase
FEBS. Lett., 580(5) 1345-1349 (2006)

2005

51
M. Mileni, F. MacMillan, C. Tziatzios, K. Zwicker, A. Haas, W. Mäntele, J. Simon, & C. R. D. Lancaster
Heterologous production in Wolinella succinogenes, isolation and characterization of the quinol:fumarate reductases from Helicobacter pylori and Campylobacter jejuni.
Biochem. Journal, Manuscript online 21.12.2005 DOI:10.1042/BJ20051675 (2005)
Biochem. Journal, 395(1), 191-201 (2006)

50
Kerstin Budiman, Fraser MacMillan,* & Hartmut Michel
Radicals in the Paracoccus denitrificans Cytochrome c Oxidase
Eur. Biophys. J., 34, 546 (2005)


49
F. Gu, N. Byrdin, F. Rappaport, A. v. d Est, F. MacMillan & K. Redding
Mutational Analysis of the two Phylloquinones in Photosystem I
in "Photosynthesis: Fundamental Aspects to Global Perpectives" (Eds. A. v.d.Est & D. Bruce), Int. Soc. Photosynth., Vol. 1, pp 101-103 (2005)


48
Fraser MacMillan (Guest Editor)
Sonderausgabe "Functional Redox Radicals in Proteins"
Biochim. Biophys. Acta - Bioenergetics, 1707, vi-vii (2005)

2004

47
F. MacMillan, C. Lange, K. Redding & C. Hunte
Resolving Protein-Quinone Interactions using pulsed EPR spectroscopy
Biochim. Biophys. Acta, 1658, 34 (2004)

46
F.G.M. Wiertz, O.-M.H. Richter, A.V. Cherepanov, F. MacMillan, B. Ludwig & S. de Vries*
An Oxo-Ferryl Tryptophan Radical Catalytic Intermediate in Cytochrome c and Quinol Oxidases trapped by Microsecond freeze-Hyperquenching (MHQ)
FEBS. Lett., 575, 127-130 (2004)

45
Y. Li, M.-G. Lucas, T. Konovalova, B. Abbott, F. MacMillan,
O. Petrenko, V. Sivakumar, R. Wang, G. Hastings, F. Gu, J. v. Tol, L.-C. Brunel, R.Timkovich, F. Rappaport, & K. Redding
Mutation of the putative hydrogen-bond donor to P₇₀₀ of Photosystem I
Biochemistry, 43 (39), 12634-12647 (2004)

44
K. Budiman, A. Kannt, S. Lyubenova, O.-M. H. Richter, B. Ludiwg, H. Michel & F. MacMillan*
Tyrosine-167: The origin of the radical species observed in the reaction of Cytochrome c Oxidase with hydrogen peroxide in Paracoccus denitrificans
Biochemistry, 43(37), 11709-11716 (2004)

43
Th. Maly, F. MacMillan, K. Zwicker, N. Kashani-Poor, U. Brandt & T. Prisner
Relaxation filtered hyperfine (REFINE) spectroscopy: A novel tool for studying overlapping biological EPR signals applied to mitochondrial Complex I
Biochemistry, 43(13) 3969-3978 (2004)

42
A. Petrenko, A. L. Maniero, J. v. Tol, F. MacMillan,
Y. Li, L.-C. Brunel & K. Redding
A high-field EPR study of P₇₀₀^+. in wild-type and mutant Photosystem I from Chlamydomonas reinhardtii
Biochemistry, 43(7) 1781-1786 (2004)

2003

41
S. Grimaldi, T. Ostermann, N. Weiden, T. Mogi, H. Miyoshi, B. Ludwig, H. Michel, T. F. Prisner & F. MacMillan^*
Asymmetric binding of the high-affinity Q_H^-. ubisemiquinone in quinol oxidase (bo₃) from E. coli studied by multifrequency EPR spectroscopy

Biochemistry, 42(19), 5632 - 5639 (2003)

40
T. Prisner, S. Lyubenova, Y. Atabay, F. MacMillan, A. Kröger, & O. Klimmek
Multifrequency cw-EPR investigation of the catalytic molybdenum cofactor of polysulfide reductase from Wolinella succinogenes
J. Biol. Inorg. Chem. , 8(4), 419 - 426 (2003)

2002

39
S. Grimaldi, F. MacMillan, T. Ostermann, B. Ludwig, H. Michel, T. Mogi, H. Miyoshi, N. Weiden, K.-P. Dinse & T. F. Prisner
Q_H^-. quinone binding pocket in quinol oxidase studied by EPR spectroscopy
Biochim. Biophys. Acta Suppl., 1555, 87 (2002)

38
Th. Maly, F. MacMillan, K. Zwicker, N. Kashani-Poor, L. Grgic, U. Brandt & T.F. Prisner
Complex I studied by pulsed EPR Spectroscopy
Biochim. Biophys. Acta Suppl., 1555, 191 (2002)

2001

37
K. Redding, R. Bittl, F. MacMillan, C. Teutloff, F. Gu, S. Grimaldi & B. Boudreaux
Mutational analysis of the binding sites of the phylloquinones in PS I
in Proceedings of the 12th International Congress on Photosynthesis (2001), Brisbane, Australia; CSIRO Publishing, ISBN 0643 06711 6 S6-029


36
Th. Maly, K. Zwicker, N. Kashani-Poor, F. MacMillan, U. Brandt & T. Prisner
Direct evidence for the nitrogen ligation of the N2 FeS-Cluster in Complex I from Yarrowia lipolytica
J. Inorg. Biochem., 86(1), 327 (2001)

35
Brent Bouderaux, Fraser MacMillan, Christian Teutloff, Rufat Agalarov, Feifei Gu, Stéphane Grimaldi, Robert Bittl, Klaus Brettel & Kevin Redding
Mutations in both sides of the photosystem I reaction centre identify the phylloquinone observed by electron paramagnetic resonance spectrscopy
J. Biol. Chem, 276(40), 37299-37306 (2001)

34
T. Strube, O. Schiemann, F. MacMillan, T. F. Prisner & J. W. Engels
A new facile method for spin-labeling of oligonucleotides
Nucleosides, Nucleotides and Nucleic Acids, 20(4), 1271-1274 (2001)

33
Thomas Prisner, Martin Rohrer & Fraser MacMillan
Pulsed EPR Spectroscopy: Biological Applications
Annual Reviews in Physical Chemistry, 52, 279-313 (2001)

32
Stéphane Grimaldi, Fraser MacMillan,* Thomas Ostermann, Bernd Ludwig, Hartmut Michel & Thomas F. Prisner
Q_H Ubisemiquinone Radical in the bo₃-Type Ubiquinol Oxidase Studied by Pulsed Electron Paramagnetic Resonance and Hyperfine Sublevel Correlation Spectroscopy
Biochemistry, 40(4), 1037-1043 (2001)

31
Peter Faller, Thorsten Maly, A. William Rutherford & Fraser MacMillan*
Chlorophyll and Carotenoid Radicals in Photosystem II Studied by Pulsed ENDOR
Biochemistry, 40(2), 320-326 (2001)

2000

30
Hanno Käß, Fraser MacMillan, Bernd Ludwig, Thomas F. Prisner
Investigaion of the Mn Binding Site in Cytochrome c Oxidase of Paracoccus denitrificans by High-Frequency EPR
J. Phys. Chem. B, 104(22), 5362-5371 (2000)

1999

29
K. E. Redding, B. G. Boudreaux, F. MacMillan, A.-L. Maniero & L.-C. Brunel
Photosystem I: A high-field EPR analysis of mutantswith altered axial ligands
National High Magnetic Field Laboratory, Annual Research Review, Vol. 1 - Research pp 23-24 (1999)

28
C. Jegerschöld, F. MacMillan, W. Lubitz & A. W. Rutherford
EPR Effects of Copper and Zinc Ions on Photosystem II Studied by EPR Spectroscopy
Biochemistry, 38(38), 12439-12445 (1999).

27
A. T. Gardiner, S. G. Zech, F. MacMillan, H. Käß, R. Bittl, E. Schlodder, F. Lendzian, and W. Lubitz.
EPR Studies of Zn-Substituted Reaction Centers from Rhodopseudomonas viridis.
Biochemistry, 38(36), 11773-11787 (1999).

26
Fraser MacMillan,* Aimo Kannt, Julia Behr, Thomas Prisner & Harmut Michel
Direct Evidence for a Tyrosine Radical in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide
Biochemistry, 38(29), 9179-9184 (1999).

1998

25
C. Teutloff, F. MacMillan, R. Bittl, F. Lendzian, and W. Lubitz.
A comparative Study of (A₁^·-) in PS I from Cyanobacteria, Green Plants and Algae using EPR and ENDOR Spectroscopy.
in Photosynthesis: Mechanisms and Effects (G. Garab, editor) Vol.I, pp. 607-610 Kluwer Academic Publisher, Dordrecht (1998)

24
K. Redding, F. MacMillan, W. Leibl, K. Brettel, A. W. Rutherford, J. Breton & J.-D. Rochaix
A Survey of Conserved Histidines in the Photosystem I Core: Methodology and Analysis of the PSAB H656L Mutant
in Photosynthesis: Mechanisms and Effects (G. Garab, editor) Vol.I, pp. 591-594 Kluwer Academic Publisher, Dordrecht (1998)

23
F. MacMillan,* M. Rohrer, J. Krzystek, L.-C. Brunel and A. W. Rutherford
A High-Field/High-Frequency EPR Characterisation of the Primary Donor (P^·+) in Bacterial and Plant Photosynthetic Reaction Centres
in Photosynthesis: Mechanisms and Effects (G. Garab, editor) Vol.I, pp. 715-718 Kluwer Academic Publisher, Dordrecht (1998)

22
M. Rohrer, F. MacMillan, J. Krzystek, L.-C. Brunel & A. W. Rutherford
High-Field / High-Frequency EPR Spectroscopy: (1) Characterisation of the Primary Donor (P^·+) in Bacterial and Plant Photosynthetic Reaction Centres. (2) Fabry-Perot Resonator for Multi-Frequency High-Field EPR at Millimeter and Submillimeter Wavelengths
in Magnetic resonance and related phenomena, proceed. of the 29. AMPERE/ 13. ISMAR (D. Ziessow, W. Lubitz & F. Lendzian, editors) Vol.II, 873-874 (1998)

21
C. Teutloff, F. MacMillan, R. Bittl, F. Lendzian & W. Lubitz
The Phylloquinone Acceptor Anion Radical in Photosystem I. A Multifrequency EPR and ENDOR Study
in Magnetic resonance and related phenomena, proceed. of the 29. AMPERE/ 13. ISMAR (D. Ziessow, W. Lubitz & F. Lendzian, editors) Vol.II, 806-807 (1998)

20
M. Knüpling, F. MacMillan & S. Un
Hydrogen bonding of semiquinone radical anions probed by 285 GHz high-field EPR
in Magnetic resonance and related phenomena, proceed. of the 29. AMPERE/ 13. ISMAR (D. Ziessow, W. Lubitz & F. Lendzian, editors) Vol.II, 802-803 (1998)

19
F. MacMillan, C. Teutloff, A. W. Rutherford & W. Lubitz
An EPR and pulsed ENDOR study of the electron acceptor anion radicals in photosystem I
in Magnetic resonance and related phenomena, proceed. of the 29. AMPERE/ 13. ISMAR (D. Ziessow, W. Lubitz & F. Lendzian, editors) Vol.II, 802-803 (1998)

18
T. Prisner, M. Rohrer, F. MacMillan, W. Lubitz & K. Mõbius
Pulsed High-Field EPR spectroscopy on proteins
in Magnetic resonance and related phenomena, proceed. of the 29. AMPERE/ 13. ISMAR (D. Ziessow, W. Lubitz & F. Lendzian, editors) Vol.I, 256-257 (1998)

17
M. Rohrer, F. MacMillan, T. F. Prisner, K. Mõbius, A. T. Gardiner & W. Lubitz
Pulsed ENDOR at 95 GHz on the Primary Acceptor Ubisemiquinone Q_A^·- in Photosynthetic Bacterial Reaction Centers and Related Model Systems
J. Phys. Chem. B, 102(23), 4648-4657 (1998).

16
Kevin Redding, Fraser MacMillan, Winfried Leibl, Klaus Brettel, Jonathan Hanley, A. William Rutherford Jacques Breton & Jean-David Rochaix
A systematic survey of conserved histidines in the core subunits of photosystem I by site-directed mutagenesis reveals the likely axial ligands of P₇₀₀
EMBO Journal, 17(1), 50-60 (1998)

1997

15
F. MacMillan, M. Rohrer, S. Un, M. Knüpling, J. Hanley, A.W. Rutherford, L.-C. Brunel
A high-field, high-frequency EPR study of radical anions and cations in membrane proteins
National High Magnetic Field Laboratory, Annual Report, Vol. 1 - Research pp 18-19 (1997)

14
G. Renger, J. Kurreck, E. Haag, F. Reifarth, A. Bergmann, F. Parak, A. Garbers, F. MacMillan, F. Lendzian & W. Lubitz
The Non-heme Iron Centre of PS II and Modulatory Effects of Exogenous Copper (II)
in Bioinorganic Chemistry: Transition Metals in Biology and their Coordination Chemistry (A. X. Trautwein, editor) pp. 160-177. VCH Publishers, Weinheim, (1997)

13
Jonathan Hanley, Yiannis Deligiannakis, Fraser MacMillan, Hervé Bottin & A. William Rutherford
ESEEM study of the phyllosemiquionone radical A₁^·- in ¹⁴N and ¹⁵N-labeled photosystem I

Biochemistry, 36(39), 11543-11549 (1997).

12
Fraser MacMillan*, Jonathan Hanley, Louise van der Weerd, Moritz Knüpling, Sun Un & A. William Rutherford
Orientation of the phylloquinone electron acceptor anion radical in photosystem I
Biochemistry, 36(31), 9297-9303 (1997).

1996

11
A. Gardiner, H. Käß, S. G. Zech, R. Bittl, F. MacMillan, F. Lendzian & W. Lubitz
EPR and ESEEM of (Q_A^·-) and transient EPR of (P₉₆₀^·+Q_A^·-) in Zn-substituted reaction centers from Rps. viridis

Biophysical Journal, 70, 11a (1996)

10

Friedhelm Lendzian, Margareta Sahlin, Fraser MacMillan, Robert Bittl, Stephan Pötsch, Britt-Marie Sjöberg, Astrin Gräslund, Wolfgang Lubitz, and Günter Lassmann
Electronic Structure of Neutral Tryptophan Radicals in Ribonucleotid Reductase Studied by EPR and ENDOR Spectroscopy
J. Am. Chem. Soc., 118(34), 8111-8120 (1996)

1995

9

A. T. Gardiner, F. Lendzian, F. MacMillan, S. G. Zech, R. Bittl, M. Kuhn, and W. Lubitz.
EPR Characterization of (Q_A^·-) from Biosynthetically and Chemically Substituted Zn(II) Reaction Centers from Rhodobacter sphaeroides and Rhodopseudomonas viridis.
In Photosynthesis: From Light to Biosphere(P. Mathis, editor), Vol.I pp. 655-658. Kluwer Academic Publishers, Dordrecht (1995)

8

F. MacMillan, J. Kurreck, N. Adir, F. Lendzian, H. Käß, F. Reifarth, G. Renger & W. Lubitz
EPR, ENDOR and ESEEM investigation of the electron acceptor raidcal anion (Q_A^·-) in photosystem II (PS II) reaction centres
in Photosynthesis: From Light to Biosphere (P. Mathis, editor) Vol.I pp. 659-662. Kluwer Academic Publishers, Dordrecht (1995)

7

Fraser MacMillan, Friedhelm Lendzian & Wolfgang Lubitz
An EPR and ENDOR characterisation of semiquinone anion radicals related to photosynthesis
Magn. Reson. in Chem., 33(Spec. Issue), S81-S93 (1995)

6

M. Rohrer, M. Plato, F. MacMillan, Y. Grishin, W. Lubitz & K. Möbius
Orientation-selected 95 GHz High-Field ENDOR spectroscopy of randomly oriented plastoquinone anion radicals
J. Magn. Reson. Series A, 116(1), 59-66 (1995)

5

Fraser MacMillan, Friedhelm Lendzian, Gernot Renger & Wolfgang Lubitz
EPR/ENDOR investigation of the primary electron acceptor radical anion (Q_A^·-) in iron-depleted Photosystem II membrane fragments
Biochemistry, 34(25), 8144-8156 (1995)

1993

4
O. Burghaus, M. Plato, M. Rohrer, K. Möbius, F. MacMillan, & W. Lubitz
3 mm high-field EPR on semiquinone radical anions related to photosynthesis and on the primary donor (P^·+) and acceptor (Q_A^·-) in reaction centres of Rhodobacter sphaeroides R-26

J. Phys. Chem., 97(29), 7639-7647 (1993)

1990

3
Tom Wydrzynski, Frank Baumgart, Fraser MacMillan & Gernot Renger
Is there a direct chloride cofactor requirement in the oxygen-evolving reactions of Photosystem II ?
Photosynthesis Research, 25(1), 59-72 (1990)

2

T. Wydrzynski, F. Baumgart, F. MacMillan, G. Renger & T. Vänngard
The chloride demand in oxygen evolution is determined by the protein structural integrity within Photosystem II
in Current Research in Photosynthesis (M. Baltscheffsky, editor) pp. 183-187. Kluwer Academic Publishers, Dordrecht (1990)

1

F. MacMillan, H. Gleiter, G. Renger & W. Lubitz
EPR/ENDOR studies of Plastoquinone anion radical in Photosystem II (Q_A^·-) and in organic solvents
in Current Research in Photosynthesis (M. Baltscheffsky, editor) pp. 531-534. Kluwer Academic Publishers, Dordrecht (1990)



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